2-[(3-Chlorophenyl)methoxy]-6-(1-piperazinyl)pyrazine hydrochloride
2-[(3-Chlorophenyl)methoxy]-6-(1-piperazinyl)pyrazine hydrochloride
CAS: 1215721-40-6
Molecular Formula: C15H18Cl2N4O
2-[(3-Chlorophenyl)methoxy]-6-(1-piperazinyl)pyrazine hydrochloride - Names and Identifiers
2-[(3-Chlorophenyl)methoxy]-6-(1-piperazinyl)pyrazine hydrochloride - Physico-chemical Properties
| Molecular Formula | C15H18Cl2N4O |
| Molar Mass | 341.23562 |
| Solubility | DMSO |
| Storage Condition | -20℃ |
2-[(3-Chlorophenyl)methoxy]-6-(1-piperazinyl)pyrazine hydrochloride - Reference
| Reference Show more | 1: Higgins GA, Silenieks LB, Altherr EB, MacMillan C, Fletcher PJ, Pratt WE. Lorcaserin and CP-809101 reduce motor impulsivity and reinstatement of food seeking behavior in male rats: Implications for understanding the anti-obesity property of 5-HT(2C) receptor agonists. Psychopharmacology (Berl). 2016 May 30. [Epub ahead of print] PubMed PMID: 27241709. 2: Jukic MM, Carrillo-Roa T, Bar M, Becker G, Jovanovic VM, Zega K, Binder EB, Brodski C. Abnormal development of monoaminergic neurons is implicated in mood fluctuations and bipolar disorder. Neuropsychopharmacology. 2015 Mar;40(4):839-48. doi: 10.1038/npp.2014.244. Epub 2014 Sep 22. PubMed PMID: 25241801; PubMed Central PMCID: PMC4330498. 3: Goda SA, Piasecka J, Olszewski M, Kasicki S, Hunt MJ. Serotonergic hallucinogens differentially modify gamma and high frequency oscillations in the rat nucleus accumbens. Psychopharmacology (Berl). 2013 Jul;228(2):271-82. doi: 10.1007/s00213-013-3057-1. Epub 2013 Mar 23. PubMed PMID: 23525524; PubMed Central PMCID: PMC3693439. 4: Canal CE, Booth RG, Morgan D. Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response model. Neuropharmacology. 2013 Jul;70:112-21. doi: 10.1016/j.neuropharm.2013.01.007. Epub 2013 Jan 23. PubMed PMID: 23353901; PubMed Central PMCID: PMC3754837. 5: Higgins GA, Silenieks LB, Lau W, de Lannoy IA, Lee DK, Izhakova J, Coen K, Le AD, Fletche |
2-[(3-Chlorophenyl)methoxy]-6-(1-piperazinyl)pyrazine hydrochloride - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.931 ml | 14.653 ml | 29.305 ml |
| 5 mM | 0.586 ml | 2.931 ml | 5.861 ml |
| 10 mM | 0.293 ml | 1.465 ml | 2.931 ml |
| 5 mM | 0.059 ml | 0.293 ml | 0.586 ml |
Last Update：2024-01-02 23:10:35
2-[(3-Chlorophenyl)methoxy]-6-(1-piperazinyl)pyrazine hydrochloride - Reference Information
| biological activity | CP-809101 hydrochloride is a 5-HT2 receptor agonist, the pEC50 for the human 5-HT2C/5-HT2B/5-HT2A receptor was 9.96/7.19/6.81, respectively. |
Last Update：2024-04-09 20:52:54
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View History
2-[(3-Chlorophenyl)methoxy]-6-(1-piperazinyl)pyrazine hydrochloride
1,3-双(3-甲氧基苯基)丙烷-1,3-二酮
MT1-MMP PRODOMAIN (CATALYTIC DOMAIN) (HIS)
3 - cyclohexene - 1 - forMic acid
Methanimidamide, monohydrobromide (9CI)
2-(甲硫基)嘧啶-4-羧酸乙酯
4-(4'-甲苯基乙炔基)苯甲醚
1,3-双(3-甲氧基苯基)丙烷-1,3-二酮
MT1-MMP PRODOMAIN (CATALYTIC DOMAIN) (HIS)
3 - cyclohexene - 1 - forMic acid
Methanimidamide, monohydrobromide (9CI)
2-(甲硫基)嘧啶-4-羧酸乙酯
4-(4'-甲苯基乙炔基)苯甲醚